MGH

Research

PERT

The CVE coordinates data collection and analysis for the MGH Pulmonary Embolism Response Team (PERT). Along with colleagues in cardiology, pulmonology and surgery, Dr. Chris Kabrhel created the first PERT in the world. The CVE has managed data collection for MGH PERT patients since the team was founded in 2012. The ongoing MGH registry now includes more than 1200 patients and investigators have published dozens of peer-reviewed manuscripts describing the treatment and outcomes of patients with severe PE.

PERT
Publications

Predicting factors for pulmonary embolism response team activation in a general pulmonary embolism population.

Mortensen CS, Kramer A, Schultz JG, Giordano N, Zheng H, Andersen A, Nielsen-Kudsk JE, Kabrhel C.J Thromb Thrombolysis. 2021 Aug 9. doi: 10.1007/s11239-021-02533-0. Online ahead of print.PMID: 34370168

Clinical factors associated with massive pulmonary embolism and PE-related adverse clinical events.

Hariharan P, Giordano N, Muzikansky A, Kabrhel C.Int J Cardiol. 2021 May 1;330:194-199. doi: 10.1016/j.ijcard.2021.01.057. Epub 2021 Jan 31.PMID: 33535077

Patient and operational factors that influence the decision to place an inferior vena cava filter in a pulmonary embolism response team.

Lun EWY, Giordano NJ, Kramer A, Mortensen CS, Torrey J, Zheng H, Kabrhel C.J Vasc Surg Venous Lymphat Disord. 2021 Jul;9(4):895-903. doi: 10.1016/j.jvsv.2020.11.021. Epub 2020 Dec 3.PMID: 33278645

Left Ventricular Dysfunction Correlates With Mortality in Pulmonary Embolism.

Liteplo AS, Huang CK, Zheng H, Patel R, Ratanski D, Giordano NJ, Kabrhel C, Shokoohi H.J Emerg Med. 2021 Feb;60(2):135-143. doi: 10.1016/j.jemermed.2020.09.041. Epub 2020 Oct 27.PMID: 33127261

The echocardiographic ratio tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure predicts short-term adverse outcomes in acute pulmonary embolism.

Lyhne MD, Kabrhel C, Giordano N, Andersen A, Nielsen-Kudsk JE, Zheng H, Dudzinski DM.Eur Heart J Cardiovasc Imaging. 2021 Feb 22;22(3):285-294. doi: 10.1093/ehjci/jeaa243.PMID: 33026070

Pulmonary embolism with clot in transit: An analysis of risk factors and outcomes.

Garvey S, Dudzinski DM, Giordano N, Torrey J, Zheng H, Kabrhel C.Thromb Res. 2020 Mar;187:139-147. doi: 10.1016/j.thromres.2020.01.006. Epub 2020 Jan 10.PMID: 31991381

Septal bowing and pulmonary artery diameter on computed tomography pulmonary angiography are associated with short-term outcomes in patients with acute pulmonary embolism.

Lyhne MD, Schultz JG, MacMahon PJ, Haddad F, Kalra M, Tso DM, Muzikansky A, Lev MH, Kabrhel C.Emerg Radiol. 2019 Dec;26(6):623-630. doi: 10.1007/s10140-019-01709-9. Epub 2019 Aug 2.PMID: 31376018

Chronic right ventricular pressure overload in acute pulmonary embolism.

Witkin A, Wilcox SR, Kabrhel C.J Crit Care. 2019 Dec;54:276. doi: 10.1016/j.jcrc.2019.05.009. Epub 2019 May 23.PMID: 3119657

Impact of chronic right ventricular pressure overload in short-term outcomes of acute pulmonary embolism: A retrospective analysis.

Witkin A, Wilcox SR, Chang Y, Huang F, Dudzinski D, Zheng H, Channick R, Kabrhel C.J Crit Care. 2019 Jun;51:1-5. doi: 10.1016/j.jcrc.2019.01.007. Epub 2019 Jan 11.PMID: 30673622

Changes in treatment and outcomes after creation of a pulmonary embolism response team (PERT), a 10-year analysis.

Rosovsky R, Chang Y, Rosenfield K, Channick R, Jaff MR, Weinberg I, Sundt T, Witkin A, Rodriguez-Lopez J, Parry BA, Harshbarger S, Hariharan P, Kabrhel C.J Thromb Thrombolysis. 2019 Jan;47(1):31-40. doi: 10.1007/s11239-018-1737-8.PMID: 30242551

Extracorporeal membrane oxygenation in acute massive pulmonary embolism: a case series and review of the literature.

Al-Bawardy R, Rosenfield K, Borges J, Young MN, Albaghdadi M, Rosovsky R, Kabrhel C.Perfusion. 2019 Jan;34(1):22-28. doi: 10.1177/0267659118786830. Epub 2018 Jul 16.PMID: 30009670

Does the Time of Day a Pulmonary Embolism Response Team Is Activated Affect Time to Intervention or Outcome?

McNeill JN, Witkin AS, Chang Y, Kabrhel C, Channick RN.Chest. 2017 Dec;152(6):1353-1354. doi: 10.1016/j.chest.2017.09.033.PMID: 29223267

Catheter-based therapies in acute pulmonary embolism.

Schultz J, Andersen A, Kabrhel C, Nielsen-Kudsk JE.EuroIntervention. 2018 Feb 20;13(14):1721-1727. doi: 10.4244/EIJ-D-17-00437.PMID: 29175770

A Pulmonary Embolism Response Team: initial experiences and future directions.

Zern EK, Young MN, Rosenfield K, Kabrhel C.Expert Rev Cardiovasc Ther. 2017 Jun;15(6):481-489. doi: 10.1080/14779072.2017.1337509. Epub 2017 Jun 5.PMID: 28571513

Comparison of Emergency Department Patients to Inpatients Receiving a Pulmonary Embolism Response Team (PERT) Activation.

Deadmon EK, Giordano NJ, Rosenfield K, Rosovsky R, Parry BA, Al-Bawardy RF, Chang Y, Kabrhel C.Acad Emerg Med. 2017 Jul;24(7):814-821. doi: 10.1111/acem.13199. Epub 2017 May 11.PMID: 28419620

Achieving Multidisciplinary Collaboration for the Creation of a Pulmonary Embolism Response Team: Creating a “Team of Rivals”.

Kabrhel C.Semin Intervent Radiol. 2017 Mar;34(1):16-24. doi: 10.1055/s-0036-1597760.PMID: 28265126

Risk factors for intracranial haemorrhage in patients with pulmonary embolism treated with thrombolytic therapy Development of the PE-CH Score.

Chatterjee S, Weinberg I, Yeh RW, Chakraborty A, Sardar P, Weinberg MD, Kabrhel C, Barnes GD, Mukherjee D, Kumbhani D, Bashir R, Vaidya A, Smith A, Fuchs B, Groeneveld P, Giri J.Thromb Haemost. 2017 Jan 26;117(2):246-251. doi: 10.1160/TH16-07-0588. Epub 2016 Nov 24.PMID: 27882375

Pulmonary Embolism Response Teams.

Witkin AS, Harshbarger S, Kabrhel C.Semin Thromb Hemost. 2016 Nov;42(8):857-864. doi: 10.1055/s-0036-1593541. Epub 2016 Oct 21.PMID: 27769084

A Multidisciplinary Pulmonary Embolism Response Team: Initial 30-Month Experience With a Novel Approach to Delivery of Care to Patients With Submassive and Massive Pulmonary Embolism.

Kabrhel C, Rosovsky R, Channick R, Jaff MR, Weinberg I, Sundt T, Dudzinski DM, Rodriguez-Lopez J, Parry BA, Harshbarger S, Chang Y, Rosenfield K.Chest. 2016 Aug;150(2):384-93. doi: 10.1016/j.chest.2016.03.011. Epub 2016 Mar 19.PMID: 27006156

The Massachusetts General Hospital Pulmonary Embolism Response Team (MGH PERT): creation of a multidisciplinary program to improve care of patients with massive and submassive pulmonary embolism.

Provias T, Dudzinski DM, Jaff MR, Rosenfield K, Channick R, Baker J, Weinberg I, Donaldson C, Narayan R, Rassi AN, Kabrhel C.Hosp Pract (1995). 2014 Feb;42(1):31-7. doi: 10.3810/hp.2014.02.1089.PMID: 24566594

A multidisciplinary pulmonary embolism response team.

Kabrhel C, Jaff MR, Channick RN, Baker JN, Rosenfield K.Chest. 2013 Nov;144(5):1738-1739. doi: 10.1378/chest.13-1562.PMID: 24189880